In order to minimize eye stress, take breaks when you have to spend long periods of time working in front of a computer. Even taking a two-minute break every half hour makes a huge difference when it comes to the toll that the work takes on your eyes, and you will be more productive.
Do you wear contacts? If so, make sure you have a pair of glasses that you can wear if your eyes get irritated. You do not want to make the situation worse by forcing yourself to wear the contacts because serious problems can result. Also, make sure you keep the contacts very clean.
The eyes tend to become dry when you get older. Omega-3 fatty acids are healthy for your eyes. Keep in mind that cold or hot air can make the issue worse. Make sure that the vents in your car are not directly on your face.